lisdexamfetamine dimesylate 50 MG Oral Capsule [Vyvanse]
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lisdexamfetamine dimesylate 50 MG Oral Capsule [Vyvanse]
50 MG · Oral Capsule · oral
A form of lisdexamfetamine dimesylate →
lisdexamfetamine dimesylate 50 MG Oral Capsule [Vyvanse] — Centrally acting sympathomimetics. Strength, form, class, interactions & more.
![lisdexamfetamine dimesylate 50 MG Oral Capsule [Vyvanse]](https://dailymed.nlm.nih.gov/dailymed/image.cfm?setid=bdb03bfa-0398-41e5-8e73-ded696cbca32&name=image-1.jpg)
Active ingredient
Classification
Centrally acting sympathomimeticsCentral Nervous System Stimulant
Drug interactions
Lisdexamfetamine dimesylate has several clinically important drug interactions that can affect its metabolism and efficacy.
- majorMAO Inhibitors (MAOI) — Increased risk of hypertensive crisis and toxic neurological effects.
- majorserotonergic drugs — Increased risk of serotonin syndrome.
- majorCYP2D6 inhibitors — Increased exposure of dextroamphetamine and risk of serotonin syndrome.
- majoralkalinizing agents — Increased blood levels and potentiation of amphetamine action.
- majoracidifying agents — Decreased blood levels and efficacy of amphetamines.
- moderatetricyclic antidepressants — Enhanced activity of tricyclic agents and increased cardiovascular effects.
Real-world adverse events (FAERS)
Drug Ineffective4,564Fatigue1,991Off Label Use1,986Anxiety1,751Headache1,707Product Availability Issue1,564Nausea1,506Insomnia1,455
Source: RxNorm + openFDA + RxClass + FAERS · 2026
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