divalproex sodium 125 MG Delayed Release Oral Capsule
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divalproex sodium 125 MG Delayed Release Oral Capsule
125 MG · Delayed Release Oral Capsule · oral
A form of divalproex →
divalproex sodium 125 MG Delayed Release Oral Capsule — Fatty acid derivatives. Strength, form, class, interactions & more.
Active ingredient
Classification
Fatty acid derivativesMood Stabilizer
Drug interactions
Divalproex has several drug interactions that can affect its clearance and the pharmacokinetics of co-administered medications.
- majorphenytoin — increased valproate clearance
- majorcarbamazepine — increased valproate clearance
- majorphenobarbital — increased valproate clearance
- majorprimidone — increased valproate clearance
- majorrifampin — increased valproate clearance
- moderatefelbamate — increased valproate peak concentration
- moderateaspirin — increased free fraction of valproate
- majorcarbapenem antibiotics — reduction in serum valproic acid concentration
- majorestrogen-containing hormonal contraceptives — decreased concentration of valproate
- moderatemethotrexate — decreased serum valproate levels
- moderatewarfarin — dosage adjustment may be necessary
- moderatezidovudine — dosage adjustment may be necessary
- unknowntopiramate — hyperammonemia and encephalopathy
- moderatecannabidiol — ALT and/or AST elevation
- moderateamitriptyline/nortriptyline — dosage adjustment may be necessary
- moderatepropofol — dosage adjustment may be necessary
- moderatelamotrigine — inhibits metabolism
- moderatediazepam — inhibits metabolism
- moderateethosuximide — inhibits metabolism
- moderatephenytoin — inhibits protein binding displacement
Source: RxNorm + openFDA + RxClass + FAERS · 2026
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