defactinib 200 MG Oral Tablet [Fakzynja]

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Clinical drug

defactinib 200 MG Oral Tablet [Fakzynja]

200 MG · Oral Tablet · oral

A form of defactinib →

defactinib 200 MG Oral Tablet [Fakzynja]. Strength, form, class, interactions & more.

defactinib 200 MG Oral Tablet [Fakzynja]

Active ingredient

defactinib →

Classification

Kinase Inhibitor

Drug interactions

Defactinib has several significant drug interactions that should be avoided to prevent adverse effects and reduced effectiveness.

  • majorstrong and moderate CYP3A4 inhibitors — increases defactinib exposure which may increase the risk of adverse reactions
  • majorstrong and moderate CYP3A4 inducers — decreases defactinib exposure which may reduce the effectiveness of FAKZYNJA
  • majorwarfarin — increased risk of bleeding and increased INR
  • majorproton pump inhibitors (PPIs) or H2 receptor antagonists — decreases defactinib exposure which may reduce the effectiveness of AVMAPKI FAKZYNJA CO-PACK

Source: RxNorm + openFDA + RxClass + FAERS · 2026

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