defactinib 200 MG Oral Tablet
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defactinib 200 MG Oral Tablet
200 MG · Oral Tablet · oral
A form of defactinib →
defactinib 200 MG Oral Tablet. Strength, form, class, interactions & more.
Active ingredient
Classification
Kinase Inhibitor
Drug interactions
Defactinib has several significant drug interactions that should be avoided to prevent adverse effects and reduced effectiveness.
- majorstrong and moderate CYP3A4 inhibitors — increases defactinib exposure which may increase the risk of adverse reactions
- majorstrong and moderate CYP3A4 inducers — decreases defactinib exposure which may reduce the effectiveness of FAKZYNJA
- majorwarfarin — increased risk of bleeding and increased INR
- majorproton pump inhibitors (PPIs) or H2 receptor antagonists — decreases defactinib exposure which may reduce the effectiveness of AVMAPKI FAKZYNJA CO-PACK
Source: RxNorm + openFDA + RxClass + FAERS · 2026
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