dabrafenib 50 MG Oral Capsule [Tafinlar]
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dabrafenib 50 MG Oral Capsule [Tafinlar]
50 MG · Oral Capsule · oral
A form of dabrafenib →
dabrafenib 50 MG Oral Capsule [Tafinlar] — B-Raf serine-threonine kinase (BRAF) inhibitors. Strength, form, class, interactions & more.
![dabrafenib 50 MG Oral Capsule [Tafinlar]](https://dailymed.nlm.nih.gov/dailymed/image.cfm?setid=fee1e6b1-e1a5-4254-9f2e-a70e0f8dbdea&name=tafinlar-01.jpg)
Active ingredient
Classification
B-Raf serine-threonine kinase (BRAF) inhibitorsKinase Inhibitor
Drug interactions
Dabrafenib has several interactions with drugs that are substrates of CYP enzymes, particularly CYP3A4 and CYP2C8.
- majorstrong inhibitors of CYP3A4 or CYP2C8 — may increase the concentration of dabrafenib
- moderatemidazolam — decreased systemic exposures
- moderateS-warfarin — decreased systemic exposures
- moderateR-warfarin — decreased systemic exposures
- moderatedexamethasone — decreased concentrations and loss of efficacy
- moderatehormonal contraceptives — decreased concentrations and loss of efficacy
Source: RxNorm + openFDA + RxClass + FAERS · 2026
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