Clinical drug
chlorpheniramine maleate 2 MG Oral Lozenge
2 MG · Oral Lozenge · oral
A form of chlorpheniramine →
chlorpheniramine maleate 2 MG Oral Lozenge — Substituted alkylamines. Strength, form, class, interactions & more.

Active ingredient
Classification
Substituted alkylaminesHistamine-1 Receptor Antagonist
Drug interactions
Chlorpheniramine has several drug interactions that may lead to increased risks or reduced efficacy of concomitant medications.
- majorphenytoin — may increase phenytoin levels and toxicity
- majorserotonergic drugs — may result in serotonin syndrome
- majorMonoamine Oxidase Inhibitors (MAOIs) — can potentiate the effects of hydrocodone
- majormuscle relaxants — may enhance respiratory depression
- moderatediuretics — may reduce the efficacy of diuretics
- majorCYP3A4 inhibitors — can increase plasma concentration of hydrocodone
- majorCYP3A4 inducers — can decrease plasma concentration of hydrocodone
- majorbenzodiazepines and other CNS depressants — can increase risk of respiratory depression and sedation
- majoralcohol — can result in increased hydrocodone plasma levels and overdose
Source: RxNorm + openFDA + RxClass + FAERS · 2026
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