Clinical drug

aspirin 500 MG Oral Tablet [Bufferin]

500 MG · Oral Tablet · oral

A form of aspirin

aspirin 500 MG Oral Tablet [Bufferin] — Other agents for local oral treatment. Strength, form, class, interactions & more.

aspirin 500 MG Oral Tablet [Bufferin]

Active ingredient

Classification

Other agents for local oral treatmentPlatelet Aggregation Inhibitor

Drug interactions

Aspirin has several drug interactions that can enhance effects or diminish effectiveness of other medications.

  • moderatemonoamine oxidase (MAO) inhibitors — enhanced CNS effects
  • majororal anticoagulants — causing bleeding
  • moderateoral antidiabetic agents and insulin — causing hypoglycemia
  • major6-mercaptopurine and methotrexate — causing bone marrow toxicity and blood dyscrasias
  • majornon-steroidal anti-inflammatory agents — increasing the risk of peptic ulceration and bleeding
  • majorother narcotic analgesics, alcohol, general anesthetics, tranquilizers, sedative-hypnotics, or other CNS depressants — causing increased CNS depression
  • moderateuricosuric agents such as probenecid and sulfinpyrazone — reducing their effectiveness in the treatment of gout

Source: RxNorm + openFDA + RxClass + FAERS · 2026

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