asciminib 100 MG Oral Tablet [Scemblix]

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Clinical drug

asciminib 100 MG Oral Tablet [Scemblix]

100 MG · Oral Tablet · oral

A form of asciminib →

asciminib 100 MG Oral Tablet [Scemblix] — BCR-ABL tyrosine kinase inhibitors. Strength, form, class, interactions & more.

asciminib 100 MG Oral Tablet [Scemblix]

Active ingredient

asciminib →

Classification

BCR-ABL tyrosine kinase inhibitors

Drug interactions

Asciminib has several interactions with CYP3A4, CYP2C9, P-gp, and BCRP substrates, which may increase the risk of adverse reactions.

  • majorstrong CYP3A4 inhibitors — increased risk of adverse reactions
  • majoritraconazole oral solution containing hydroxypropyl-β-cyclodextrin — reduced efficacy of SCEMBLIX
  • moderatestrong CYP3A4 inducers — decreased plasma concentrations of asciminib
  • majorcertain CYP3A4 substrates — increased risk of adverse reactions
  • majorCYP2C9 substrates — increased risk of adverse reactions
  • moderatecertain P-gp substrates — increased risk of adverse reactions
  • majorrosuvastatin — increased risk of adverse reactions

Real-world adverse events (FAERS)

Fatigue236Death170Nausea170Drug Ineffective162Thrombocytopenia146Headache123Diarrhoea122Drug Intolerance121

Source: RxNorm + openFDA + RxClass + FAERS · 2026

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