abemaciclib 50 MG Oral Tablet [Verzenio]
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abemaciclib 50 MG Oral Tablet [Verzenio]
50 MG · Oral Tablet · oral
A form of abemaciclib →
abemaciclib 50 MG Oral Tablet [Verzenio] — Cyclin-dependent kinase (CDK) inhibitors. Strength, form, class, interactions & more.
![abemaciclib 50 MG Oral Tablet [Verzenio]](https://dailymed.nlm.nih.gov/dailymed/image.cfm?setid=be4bc0de-0fdc-4d46-8d25-be43c79e6a06&name=verzenio-100mg-14ct-031-02.jpg)
Active ingredient
Classification
Cyclin-dependent kinase (CDK) inhibitorsKinase Inhibitor
Drug interactions
Abemaciclib has significant interactions with CYP3A inhibitors and inducers, which can affect its exposure and efficacy.
- majorketoconazole — increased toxicity
- majorstrong CYP3A inhibitors — increased toxicity
- moderatemoderate CYP3A inhibitors — adverse reactions possible
- majorstrong CYP3A inducers — reduced activity
- majormoderate CYP3A inducers — reduced activity
- majorgrapefruit products — increased toxicity
Real-world adverse events (FAERS)
Diarrhoea5,680Fatigue2,311Nausea1,967Vomiting1,055Malignant Neoplasm Progression1,040Decreased Appetite875Asthenia783Death753
Source: RxNorm + openFDA + RxClass + FAERS · 2026
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