abemaciclib 200 MG Oral Tablet

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Clinical drug

abemaciclib 200 MG Oral Tablet

200 MG · Oral Tablet · oral

A form of abemaciclib →

abemaciclib 200 MG Oral Tablet — Cyclin-dependent kinase (CDK) inhibitors. Strength, form, class, interactions & more.

abemaciclib 200 MG Oral Tablet

Active ingredient

Classification

Cyclin-dependent kinase (CDK) inhibitorsKinase Inhibitor

Drug interactions

Abemaciclib has significant interactions with CYP3A inhibitors and inducers, which can affect its exposure and efficacy.

  • majorketoconazole — increased toxicity
  • majorstrong CYP3A inhibitors — increased toxicity
  • moderatemoderate CYP3A inhibitors — adverse reactions possible
  • majorstrong CYP3A inducers — reduced activity
  • majormoderate CYP3A inducers — reduced activity
  • majorgrapefruit products — increased toxicity

Real-world adverse events (FAERS)

Diarrhoea5,680Fatigue2,311Nausea1,967Vomiting1,055Malignant Neoplasm Progression1,040Decreased Appetite875Asthenia783Death753

Source: RxNorm + openFDA + RxClass + FAERS · 2026

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