Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders

The National Heart, Lung, and Blood Institute (NHLBI) provides global leadership for a research, training, and education program to promote the prevention and treatment of heart, lung, and blood diseases and enhance the health of all individuals so that they can live longer and more fulfilling lives. The Center for Translation Research and Implementation Science (CTRIS) plans, fosters, and supports late-stage research to identify promising approaches for ensuring successful integration of evidence and evidence-based interventions within clinical and public health settings, such as health centers, worksites, schools, and communities in the United States and abroad. These approaches build on the successes in fundamental discovery science and early-stage translational research to ensure findings achieve maximal benefit for people and their communities. They also will help tackle new challenges in late-stage T4 translation research—the phase in the translational research pathway that leads to general knowledge about implementing evidence and evidence-based interventions—that helps turn discoveries into improved health. CTRIS is the strategic focal point within NHLBI to catalyze opportunities for rigorous dissemination and implementation research to advance the creation, evaluation, reporting, dissemination, sustained adoption, spread, and scale of evidence-based interventions for the prevention and treatment of heart, lung, blood, and sleep disorders. CTRIS is charged with integrating the domain expertise found in all NHLBI organizational units and leveraging the NIH-wide investments in dissemination and implementation research to accomplish its mission.