Rare diseases · Sign or symptom
Weakness of facial musculature
Decreased facial muscle strength
HP:0030319
What it means
Reduced strength of one or more muscles innervated by the facial nerve (the seventh cranial nerve).
Rare diseases that can present with this31
Common30–79%
14- Adenylosuccinate synthetase-like 1-related distal myopathy
- Adult-onset chronic progressive external ophthalmoplegia with mitochondrial myopathy
- Autosomal dominant mitochondrial myopathy with exercise intolerance
- Bilateral perisylvian polymicrogyria
- Classic multiminicore myopathy
- Congenital fiber-type disproportion myopathy
- Facioscapulohumeral dystrophy
- Mitochondrial myopathy-cerebellar ataxia-pigmentary retinopathy syndrome
- Myasthenia gravis
- Oculopharyngeal muscular dystrophy
- Progressive external ophthalmoplegia-myopathy-emaciation syndrome
- Proximal spinal muscular atrophy
- Steinert myotonic dystrophy
- X-linked centronuclear myopathy
Sometimes5–29%
14- Autosomal recessive distal nebulin myopathy
- Bickerstaff brainstem encephalitis
- Charcot-Marie-Tooth disease type 1F
- Charcot-Marie-Tooth disease type 4B2
- Charcot-Marie-Tooth disease type 4C
- Desminopathy
- FLNC-related handgrip and calf weakness-distal myopathy
- Infantile-onset X-linked spinal muscular atrophy
and 6 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Decreased strength of facial muscles · Face weakness · Facial muscle weakness · Facial weakness · Myasthenia of facial muscles · Reduced facial muscle strength · Weakness of face
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.