Rare diseases · Sign or symptom
Long face
Elongation of face
HP:0000276
What it means
Facial height (length) is more than 2 standard deviations above the mean (objective); or, an apparent increase in the height (length) of the face (subjective).
Objective measurement of the face height is made with sliding calipers from the nasion, just above the depth of the nasal root, to the gnathion, the inferior border of the mandible, both in the midline. Note that long face is distinct from narrow face.
Rare diseases that can present with this104
Very common80–99%
24- Acromegaly
- Autosomal recessive faciodigitogenital syndrome
- Cardiofaciocutaneous syndrome
- CEDNIK syndrome
- Christianson syndrome
- CK syndrome
- Distal deletion 19p syndrome
- Dysmorphism-cleft palate-loose skin syndrome
- Flat face-microstomia-ear anomaly syndrome
- Harrod syndrome
- Intellectual disability-dysmorphism-hypogonadism-diabetes mellitus syndrome
- Keutel syndrome
- Koolen-De Vries syndrome
- Maternal uniparental disomy of chromosome 9 syndrome
- Megalencephaly-severe kyphoscoliosis-overgrowth syndrome
- Microbrachycephaly-ptosis-cleft lip syndrome
- Nance-Horan syndrome
- Neurodevelopmental disorder-craniofacial dysmorphism-cardiac defect-skeletal anomalies syndrome
- Peters plus syndrome
- Somatomammotropinoma
- Velo-facial-skeletal syndrome
- X-linked intellectual disability, Golabi-Ito-Hall type
- X-linked intellectual disability-hypotonia-facial dysmorphism-aggressive behavior syndrome
- X-linked intellectual disability, Siderius type
Common30–79%
41- 19p13.13microdeletion syndrome
- 19p13.3microduplication syndrome
- 19q13.11microdeletion syndrome
- 22q11.2deletion syndrome
- 5q22microdeletion syndrome
- Allan-Herndon-Dudley syndrome
- Aneurysm-osteoarthritis syndrome
- Arterial tortuosity syndrome
- Autosomal recessive multiple pterygium syndrome
- Cap myopathy
- Cardiac anomalies-short stature-joint hypermobility-facial dysmorphism syndrome
- Cockayne syndrome type 1
- Cockayne syndrome type 2
- Deafness with labyrinthine aplasia, microtia, and microdontia
- Early-onset seizures-distal limb anomalies-facial dysmorphism-global developmental delay syndrome
- Fragile X syndrome
- Fried syndrome
- Isolated Joubert syndrome
- Joubert syndrome with hepatic defect
- Joubert syndrome with ocular anomaly
- Joubert syndrome with oculorenal defect
- Joubert syndrome with renal defect
- Macrocephaly-intellectual disability-left ventricular non compaction syndrome
- Mitochondrial myopathy-cerebellar ataxia-pigmentary retinopathy syndrome
- Mosaic trisomy 8 syndrome
- Mowat-Wilson syndrome
- Neurodevelopmental disorder-craniofacial dysmorphism-cardiac defect-skeletal anomalies syndrome due to 9q21.3 microdeletion
- Neurodevelopmental disorder-craniofacial dysmorphism-cardiac defect-skeletal anomalies syndrome due to a point mutation
- Non-progressive cerebellar ataxia with intellectual disability
- Oculocerebrofacial syndrome, Kaufman type
- Oculocerebrorenal syndrome of Lowe
- Orofaciodigital syndrome type 6
- Otodental syndrome
- PMM2-CDG
- Renpenning syndrome
- Ring chromosome 22 syndrome
- Sotos syndrome
- Temtamy syndrome
- X-linked intellectual disability-global development delay-facial dysmorphism-sacral caudal remnant syndrome
- X-linked intellectual disability, Porteous type
- X-linked intellectual disability, Snyder type
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Increased height of face · Increased length of face · Increased vertical dimension of face · Long facies · Vertical elongation of face · Vertical enlargement of face · Vertical excess of face · Vertical Facial Excess
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.