Rare diseases · Sign or symptom
Finger syndactyly
HP:0006101
What it means
Webbing or fusion of the fingers, involving soft parts only or including bone structure. Bony fusions are referred to as "bony" Syndactyly if the fusion occurs in a radio-ulnar axis. Fusions of bones of the fingers in a proximo-distal axis are referred to as "Symphalangism".
Rare diseases that can present with this144
Very common80–99%
38- Acrofacial dysostosis, Catania type
- Acrofacial dysostosis, Palagonia type
- Acropectoral syndrome
- Acropectorovertebral dysplasia
- ADULT syndrome
- Apert syndrome
- Autosomal recessive faciodigitogenital syndrome
- Autosomal recessive multiple pterygium syndrome
- Bartsocas-Papas syndrome
- Blepharonasofacial malformation syndrome
- Camptodactyly-joint contractures-facial skeletal defects syndrome
- Cenani-Lenz syndrome
- Charlie M syndrome
- Cleft lip/palate-ectodermal dysplasia syndrome
- Craniodigital-intellectual disability syndrome
- Craniosynostosis, Herrmann-Opitz type
- Craniosynostosis, Philadelphia type
- Crossed polysyndactyly
- Curry-Jones syndrome
- Diaphragmatic defect-limb deficiency-skull defect syndrome
- Facial dysmorphism-anorexia-cachexia-eye and skin anomalies syndrome
- Femur-fibula-ulna complex
- Fibulo-ulnar hypoplasia-renal anomalies syndrome
- Fraser syndrome
- Hypertelorism-hypospadias-polysyndactyly syndrome
- Laurence-Moon syndrome
- Laurin-Sandrow syndrome
- Lenz-Majewski hyperostotic dysplasia
- Megalencephaly-capillary malformation-polymicrogyria syndrome
- Mesoaxial synostotic syndactyly with phalangeal reduction
- Microphthalmia with limb anomalies
- Oculodentodigital dysplasia
- Orofaciodigital syndrome type 4
- Radioulnar synostosis-microcephaly-scoliosis syndrome
- Saethre-Chotzen syndrome
- Sclerosteosis
- Syndactyly type 3
- White forelock with malformations
Common30–79%
41- 19q13.11microdeletion syndrome
- 2q37microdeletion syndrome
- 6p22microdeletion syndrome
- Aarskog-Scott syndrome
- Adams-Oliver syndrome
- Alopecia-contractures-dwarfism-intellectual disability syndrome
- Aphalangy-hemivertebrae-urogenital-intestinal dysgenesis syndrome
- Autosomal dominant popliteal pterygium syndrome
- Blepharo-cheilo-odontic syndrome
- Boomerang dysplasia
- Brachydactyly type B2
- Camptobrachydactyly
- Cohen syndrome
- Crane-Heise syndrome
- Cranioectodermal dysplasia
- Craniofrontonasal dysplasia
- Deafness-genital anomalies-metacarpal and metatarsal synostosis syndrome
- Ectrodactyly-polydactyly syndrome
- EEM syndrome
- Epiphyseal dysplasia-hearing loss-dysmorphism syndrome
- FATCO syndrome
- Greig cephalopolysyndactyly syndrome
- Hypoglossia-hypodactyly syndrome
- Intellectual disability-spasticity-ectrodactyly syndrome
- Isolated split hand-split foot malformation
- Jacobsen syndrome
- Kindler epidermolysis bullosa
- Microphthalmia, Lenz type
- Monosomy 13q14 syndrome
- Orofaciodigital syndrome type 1
- Orofaciodigital syndrome type 2
- Pfeiffer syndrome
- Pfeiffer syndrome type 1
- Pfeiffer syndrome type 2
- Pfeiffer syndrome type 3
- Postaxial acrofacial dysostosis
- Proteus syndrome
- Short stature-craniofacial anomalies-genital hypoplasia syndrome
- Simpson-Golabi-Behmel syndrome
- SPECC1L-related hypertelorism syndrome
- Symphalangism with multiple anomalies of hands and feet
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Partial syndactyly
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.