Laryngotracheoesophageal cleft

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Laryngotracheoesophageal cleft

ORPHA:2004Morphological anomaly

Also called LC · LTEC · Laryngo-tracheo-esophageal cleft · Laryngo-tracheo-esophageal diastema

What it is

A laryngo-tracheo-esophageal cleft (LC) is a congenital malformation characterized by an abnormal, posterior, sagittal communication between the larynx and the pharynx, possibly extending downward between the trachea and the esophagus.

Key facts

Prevalence
1-9 / 100 000 (at birth, Europe)
Age of onset
Antenatal, Neonatal
Inheritance
Autosomal dominant, Not applicable
Classified as
Morphological anomaly

Prevalence figures describe populations, not individuals, and are often estimates from a single study. Where the figure is an incidence or a birth prevalence, it says so.

Signs and symptoms

These ranges are how often a sign appears across everyone diagnosed, not a prediction for one person — most people have some of these and not others. Orphanet also records findings that are specifically absent in this disease; those are in the data but not listed here.

ICD-10 codes

Q32.1filed under a broader ICD-10 category — shared with 8 other rare diseases

ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. A shared code identifies the group, not this disease — the ORPHAcode above is what identifies it.

Cross-references

GARD 3188MESH C537875MONDO 0016060OMIM 215800UMLS C1840311

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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