Rare diseases · Sign or symptom
Spastic dysarthria
HP:0002464
What it means
A type of dysarthria related to bilateral damage of the upper motor neuron tracts of the pyramidal and extra- pyramidal tracts. Speech of affected individuals is slow, effortful, and has a harsh vocal quality.
Rare diseases that can present with this23
Common30–79%
21- Autosomal dominant spastic ataxia type 1
- Autosomal dominant spastic paraplegia type 9B
- Autosomal recessive cerebellar ataxia-pyramidal signs-nystagmus-oculomotor apraxia syndrome
- Autosomal recessive cerebellar ataxia with late-onset spasticity
- Autosomal recessive spastic ataxia with leukoencephalopathy
- Autosomal recessive spastic paraplegia type 20
- Autosomal recessive spastic paraplegia type 69
- Autosomal recessive spinocerebellar ataxia-blindness-deafness syndrome
- Childhood-onset spasticity with hyperglycinemia
- Early-onset spastic ataxia-myoclonic epilepsy-neuropathy syndrome
- Inherited Creutzfeldt-Jakob disease
- Juvenile primary lateral sclerosis
- Primary lateral sclerosis
- Progressive supranuclear palsy-pure akinesia with gait freezing syndrome
- Severe intellectual disability and progressive spastic paraplegia
- Spinocerebellar ataxia type 25
- Spinocerebellar ataxia type 8
- Spinocerebellar ataxia with axonal neuropathy type 1
- Tremor-ataxia-central hypomyelination syndrome
- X-linked non progressive cerebellar ataxia
- X-linked progressive cerebellar ataxia
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Rigid dysarthria
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.