Rare diseases · Sign or symptom
Severe expressive language delay
HP:0006863
What it means
A severe delay in the acquisition of the ability to use language to communicate needs, wishes, or thoughts.
Rare diseases that can present with this11
Very common80–99%
1Common30–79%
6- Bohring-Opitz syndrome
- Inverted duplicated chromosome 15 syndrome
- Microcephaly-intellectual disability-sensorineural hearing loss-epilepsy-abnormal muscle tone syndrome
- Progressive spondyloepimetaphyseal dysplasia-short stature-short fourth metatarsals-intellectual disability syndrome
- Proximal 16p11.2 microdeletion syndrome
- White-Sutton syndrome
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.