Rare diseases · Sign or symptom
Progressive psychomotor deterioration
HP:0007272
Rare diseases that can present with this12
Very common80–99%
2Common30–79%
8- Autosomal recessive cerebelloparenchymal disorder type 3
- Cerebrotendinous xanthomatosis
- Gamma-aminobutyric acid transaminase deficiency
- Gaucher disease type 2
- Isolated succinate-CoQ reductase deficiency
- Maternal uniparental disomy of chromosome 1 syndrome
- Paternal uniparental disomy of chromosome 1 syndrome
- Progressive myoclonic epilepsy type 3
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Progressive mental and motor deterioration
Progressive psychomotor deterioration
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.