Rare diseases · Sign or symptom
Poor fine motor coordination
HP:0007010
What it means
An abnormality of the ability (skills) to perform a precise movement of small muscles with the intent to perform a specific act. Fine motor skills are required to mediate movements of the wrists, hands, fingers, feet, and toes.
Rare diseases that can present with this35
Very common80–99%
3Common30–79%
16- 17p11.2microduplication syndrome
- Autosomal dominant Charcot-Marie-Tooth disease type 2A2
- Autosomal dominant Charcot-Marie-Tooth disease type 2Y
- Autosomal recessive spastic paraplegia type 55
- Congenital cerebellar ataxia due to RNU12 mutation
- Congenital-onset Steinert myotonic dystrophy
- Familial congenital mirror movements
- Friedreich ataxia
- Huntington disease
- Isolated childhood apraxia of speech
- Mowat-Wilson syndrome due to a ZEB2 point mutation
- Mowat-Wilson syndrome due to monosomy 2q22
- Retinitis pigmentosa-juvenile cataract-short stature-intellectual disability syndrome
- Steinert myotonic dystrophy
- Tay-Sachs disease
- Unilateral polymicrogyria
Sometimes5–29%
16- Alström syndrome
- Cirrhosis-dystonia-polycythemia-hypermanganesemia syndrome
- Distal deletion 10q syndrome
- Dravet syndrome
- Genetic epilepsy with febrile seizure plus
- GNB5-related intellectual disability-cardiac arrhythmia syndrome
- Huntington disease-like 1
- Lead poisoning
and 8 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions, and Orphanet separately records 2 diseases where this sign is specifically absent. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Fine motor disability · Fine motor impairment · Fine motor skill dysfunction · Impaired fine motor skills
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.