Rare diseases · Sign or symptom
Incoordination
Difficulties in coordination
HP:0002311
What it means
A deficit in coordination of muscle movements. Coordination is defined as the orchestrated movement of multiple body parts as required to accomplish intended actions, like walking.
Incoordination can result from a variety of problems affecting motor control-cerebellar dysfunction, sensory deficits, vestibular issues, or muscle weakness.
Rare diseases that can present with this45
Very common80–99%
6Common30–79%
17- 2q23.1microduplication syndrome
- Autosomal recessive cerebelloparenchymal disorder type 3
- Choreoacanthocytosis
- Cono-spondylar dysplasia
- Episodic ataxia type 4
- Glutaryl-CoA dehydrogenase deficiency
- Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome
- Monosomy 18q syndrome
- Myoclonic epilepsy of infancy
- Paraneoplastic sensory ganglionopathy
- Primary lateral sclerosis
- Progressive encephalopathy-severe neurodegeneration-lipodystrophy syndrome
- Recurrent metabolic encephalomyopathic crises-rhabdomyolysis-cardiac arrhythmia-intellectual disability syndrome
- Retinitis pigmentosa-juvenile cataract-short stature-intellectual disability syndrome
- Sandhoff disease, juvenile form
- SYNGAP1-related developmental and epileptic encephalopathy
- Tay-Sachs disease
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Incoordination of limb movements · Limb incoordination · Poor coordination · Poor motor coordination
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.