Rare diseases · Sign or symptom
Platyspondyly
Flattened vertebrae
HP:0000926
What it means
A flattened vertebral body shape with reduced distance between the vertebral endplates.
Rare diseases that can present with this78
Very common80–99%
34- Autosomal dominant brachyolmia
- Blomstrand lethal chondrodysplasia
- Brachydactylous dwarfism, Mseleni type
- Brachyolmia, Maroteaux type
- Cardiomyopathy-cataract-hip spine disease syndrome
- Chondroectodermal dysplasia with night blindness
- Cloverleaf skull-multiple congenital anomalies syndrome
- Dentinogenesis imperfecta-short stature-hearing loss-intellectual disability syndrome
- Dysosteosclerosis
- Greenberg dysplasia
- Microcephalic osteodysplastic dysplasia, Saul-Wilson type
- Myhre syndrome
- Odontochondrodysplasia
- Osteoporosis-oculocutaneous hypopigmentation syndrome
- Platyspondylic dysplasia, Torrance type
- Progressive pseudorheumatoid dysplasia
- Progressive spondyloepimetaphyseal dysplasia-short stature-short fourth metatarsals-intellectual disability syndrome
- Pseudodiastrophic dysplasia
- SPONASTRIME dysplasia
- Spondylocamptodactyly syndrome
- Spondyloenchondrodysplasia
- Spondyloepimetaphyseal dysplasia, Irapa type
- Spondyloepiphyseal dysplasia-craniosynostosis-cleft palate-cataracts-intellectual disability syndrome
- Spondyloepiphyseal dysplasia, Kimberley type
- Spondyloepiphyseal dysplasia tarda
- Spondylometaphyseal dysplasia, A4 type
- Spondylometaphyseal dysplasia-cone-rod dystrophy syndrome
- Spondylometaphyseal dysplasia, Kozlowski type
- Spondylometaphyseal dysplasia, Sedaghatian type
- Spondylo-ocular syndrome
- Thanatophoric dysplasia
- Thanatophoric dysplasia type 1
- Thanatophoric dysplasia type 2
- X-linked dominant chondrodysplasia, Chassaing-Lacombe type
Common30–79%
24- Axial spondylometaphyseal dysplasia
- Cantú syndrome
- Dyggve-Melchior-Clausen disease
- Dysplastic cortical hyperostosis, Al-Gazali type
- Dysspondyloenchondromatosis
- Hall-Riggs syndrome
- Kniest dysplasia
- Lethal Kniest-like dysplasia
- Metaphyseal chondromatosis with D-2-hydroxyglutaric aciduria
- Mucopolysaccharidosis type 4
- Occipital horn syndrome
- Pseudoachondroplasia
- Schimke immuno-osseous dysplasia
- Schwartz-Jampel syndrome
- SLC39A13-related spondylodysplastic Ehlers-Danlos syndrome
- Spondylodysplastic Ehlers-Danlos syndrome
- Spondyloepimetaphyseal dysplasia, Handigodu type
- Spondyloepimetaphyseal dysplasia, Shohat type
- Spondyloepimetaphyseal dysplasia with joint laxity, leptodactylic type
- Spondyloepiphyseal dysplasia congenita
- Spondyloepiphyseal dysplasia tarda, Kohn type
- Spondylometaphyseal dysplasia, Schmidt type
- Stickler syndrome
- Stickler syndrome type 1
Sometimes5–29%
19- Alpha-mannosidosis, infantile form
- Atelosteogenesis type I
- Autosomal recessive otospondylomegaepiphyseal dysplasia
- Autosomal recessive Stickler syndrome
- B3GALT6-related spondylodysplastic Ehlers-Danlos syndrome
- Bruck syndrome
- Geroderma osteodysplastica
- GM1 gangliosidosis
and 11 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Flat vertebral bodies · Flattened vertebral bodies
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.