Rare diseases · Sign or symptom
Intention tremor
HP:0002080
What it means
A type of kinetic tremor that occurs during target directed movement is called intention tremor. That is, an oscillatory cerebellar ataxia that tends to be absent when the limbs are inactive and during the first part of voluntary movement but worsening as the movement continues and greater precision is required (e.g., in touching a target such as the patient's nose or a physician's finger).
Rare diseases that can present with this46
Very common80–99%
3Common30–79%
21- Acute infantile liver failure-cerebellar ataxia-peripheral sensory motor neuropathy syndrome
- Ataxia-telangiectasia-like disorder
- Autosomal recessive cerebellar ataxia due to CWF19L1 deficiency
- Autosomal recessive spastic paraplegia type 77
- Cerebellar ataxia, Cayman type
- Cerebellar ataxia with neuropathy and bilateral vestibular areflexia syndrome
- Cockayne syndrome type 3
- Combined immunodeficiency with facio-oculo-skeletal anomalies
- Congenital cerebellar ataxia due to RNU12 mutation
- Friedreich ataxia
- Medulloblastoma
- Myoclonus-cerebellar ataxia-deafness syndrome
- Parkinsonian-pyramidal syndrome
- Progressive myoclonic epilepsy type 1
- RARS-related autosomal recessive hypomyelinating leukodystrophy
- Spinocerebellar ataxia type 10
- Spinocerebellar ataxia type 35
- Spinocerebellar ataxia type 40
- Tremor-ataxia-central hypomyelination syndrome
- X-linked non progressive cerebellar ataxia
- X-linked progressive cerebellar ataxia
Sometimes5–29%
17- Adult-onset autosomal dominant leukodystrophy
- Adult-onset autosomal recessive cerebellar ataxia
- Autosomal recessive spastic ataxia of Charlevoix-Saguenay
- Autosomal spastic paraplegia type 58
- Brain-lung-thyroid syndrome
- Cockayne syndrome
- Congenital cataracts-facial dysmorphism-neuropathy syndrome
- Early-onset X-linked optic atrophy
and 9 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions, and Orphanet separately records 1 disease where this sign is specifically absent. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Cerebellar tremor · Terminal tremor
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.