Rare diseases · Sign or symptom
High, narrow palate
Narrow, high-arched roof of mouth
HP:0002705
What it means
The presence of a high and narrow palate.
Rare diseases that can present with this92
Very common80–99%
16- 15q overgrowth syndrome
- 6q terminal deletion syndrome
- Cardiospondylocarpofacial syndrome
- Cleidocranial dysplasia
- Cohen syndrome
- Distal deletion 9p syndrome
- Flat face-microstomia-ear anomaly syndrome
- Intellectual disability-seizures-macrocephaly-obesity syndrome
- Lateral meningocele syndrome
- Mesomelia-synostoses syndrome
- Microcephaly-brachydactyly-kyphoscoliosis syndrome
- Nicolaides-Baraitser syndrome
- Radio-renal syndrome
- Shprintzen-Goldberg syndrome
- Sialuria
- Velo-facial-skeletal syndrome
Common30–79%
37- 16p12.1p12.3triplication syndrome
- 3C syndrome
- Acrootoocular syndrome
- Anophthalmia-megalocornea-cardiopathy-skeletal anomalies syndrome
- Autosomal dominant Robinow syndrome
- Bainbridge-Ropers syndrome
- Birk-Barel syndrome
- Cardiocranial syndrome, Pfeiffer type
- DPM1-CDG
- Ear-patella-short stature syndrome
- Familial anetoderma
- Hallermann-Streiff syndrome
- Hydrocephaly-tall stature-joint laxity syndrome
- Intellectual disability-seizures-hypophosphatasia-ophthalmic-skeletal anomalies syndrome
- Koolen-De Vries syndrome
- Macrocephaly-intellectual disability-left ventricular non compaction syndrome
- Marfan syndrome
- Microcephaly-cardiac defect-lung malsegmentation syndrome
- Monosomy X syndrome
- Mosaic monosomy X syndrome
- Muenke syndrome
- Neonatal Marfan syndrome
- Occipital horn syndrome
- Oculocerebrofacial syndrome, Kaufman type
- Oculo-palato-cerebral syndrome
- Oculopharyngodistal myopathy
- Orofaciodigital syndrome type 4
- Osteopathia striata-cranial sclerosis syndrome
- Pachydermoperiostosis
- Perlman syndrome
- Progressive essential tremor-speech impairment-facial dysmorphism-intellectual disability-abnormal behavior syndrome
- Simpson-Golabi-Behmel syndrome
- Trisomy 13 syndrome
- Turner syndrome
- Turner syndrome due to structural X chromosome anomalies
- Ventricular extrasystoles with syncopal episodes-perodactyly-Robin sequence syndrome
- Yunis-Varon syndrome
Sometimes5–29%
26- 11q22.2q22.3microdeletion syndrome
- 8p inverted duplication/deletion syndrome
- Acrofacial dysostosis, Palagonia type
- Acropectorovertebral dysplasia
- Basel-Vanagaite-Smirin-Yosef syndrome
- Carnitine palmitoyl transferase II deficiency, neonatal form
- Cenani-Lenz syndrome
- Congenital adrenal hyperplasia due to cytochrome P450 oxidoreductase deficiency
and 18 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Gothic palate · High narrow palate · High vaulted palate · Narrow and high arched palate · Narrow, high-arched palate · Narrow, highly arched palate · Narrow, highly arched roof of mouth
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.