Rare diseases · Sign or symptom
Growth delay
Delayed growth
HP:0001510
What it means
A deficiency or slowing down of growth pre- and postnatally.
Poor or abnormally slow gains in weight or height in a child.
Rare diseases that can present with this285
Very common80–99%
78- 19q13.11microdeletion syndrome
- 1q41q42microdeletion syndrome
- 20q13.33microdeletion syndrome
- 2p21microdeletion syndrome
- 4q21microdeletion syndrome
- 5q35microduplication syndrome
- Achalasia-microcephaly syndrome
- Alobar holoprosencephaly
- Ankyloblepharon-ectodermal defects-cleft lip/palate syndrome
- Aromatase deficiency
- Autosomal recessive generalized dystrophic epidermolysis bullosa, intermediate form
- Autosomal recessive generalized dystrophic epidermolysis bullosa, severe form
- Autosomal recessive hypophosphatemic rickets
- Autosomal recessive malignant osteopetrosis
- Autosomal recessive primary microcephaly
- Axial spondylometaphyseal dysplasia
- B4GALT7-related spondylodysplastic Ehlers-Danlos syndrome
- Baller-Gerold syndrome
- Baraitser-Winter cerebrofrontofacial syndrome
- Bloom syndrome
- BRESEK syndrome
- Cardiocranial syndrome, Pfeiffer type
- Cernunnos-XLF deficiency
- Cockayne syndrome
- Desmosterolosis
- Developmental delay-language impairment-dopa responsive dystonia-parkinsonism syndrome due to 2q24 microdeletion
- Dilated cardiomyopathy with ataxia
- Early-onset progressive diffuse brain atrophy-microcephaly-muscle weakness-optic atrophy syndrome
- Ear-patella-short stature syndrome
- Familial dysautonomia
- FOXG1 syndrome due to 14q12 microdeletion
- Freeman-Sheldon syndrome
- Galactose epimerase deficiency
- Gaucher disease type 1
- Glycogen storage disease due to glucose-6-phosphatase deficiency type Ib
- Growth delay due to insulin-like growth factor I resistance
- Growth delay-intellectual disability-hepatopathy syndrome
- Holocarboxylase synthetase deficiency
- Hypohidrotic ectodermal dysplasia with immunodeficiency
- Hypotonia-cystinuria syndrome
- Infantile nephropathic cystinosis
- Infantile systemic hyalinosis
- Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome
- Jacobsen syndrome
- LIG4 syndrome
- Marden-Walker syndrome
- MEHMO syndrome
- Microcephaly-microcornea syndrome, Seemanova type
- Microgastria-limb reduction defect syndrome
- Midline interhemispheric variant of holoprosencephaly
- Miller-Dieker syndrome
- Monosomy 13q34 syndrome
- Monosomy X syndrome
- Mosaic monosomy X syndrome
- Non-acquired isolated growth hormone deficiency
- Noonan syndrome with multiple lentigines
- Parana hard skin syndrome
- Pili torti-developmental delay-neurological abnormalities syndrome
- Pitt-Hopkins syndrome
- Prader-Willi syndrome
- Primary Fanconi renotubular syndrome
- Primary hypergonadotropic hypogonadism-partial alopecia syndrome
- Prominent glabella-microcephaly-hypogenitalism syndrome
- Pseudoprogeria syndrome
- Pyruvate dehydrogenase deficiency
- Rhizomelic chondrodysplasia punctata
- Ring chromosome 13 syndrome
- Semilobar holoprosencephaly
- Severe generalized junctional epidermolysis bullosa
- Short stature, Brussels type
- Short stature due to GHSR deficiency
- Short stature due to partial GHR deficiency
- Short stature due to primary acid-labile subunit deficiency
- Smith-Lemli-Opitz syndrome
- Spondyloepiphyseal dysplasia congenita
- Spondylometaphyseal dysplasia, Kozlowski type
- STAT1-related autoimmune enteropathy and endocrinopathy-susceptibility to chronic infections syndrome
- Thyroid hemiagenesis
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions, and Orphanet separately records 6 diseases where this sign is specifically absent. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Growth deficiency · Growth failure · Growth retardation · Poor growth · Retarded growth · Very poor growth
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.