Rare diseases · Sign or symptom
Difficulty running
HP:0009046
What it means
Reduced ability to run.
Rare diseases that can present with this26
Common30–79%
19- Adenylosuccinate synthetase-like 1-related distal myopathy
- Autosomal dominant Charcot-Marie-Tooth disease type 2A2
- Autosomal dominant Charcot-Marie-Tooth disease type 2E
- Autosomal dominant Charcot-Marie-Tooth disease type 2Y
- Autosomal dominant Charcot-Marie-Tooth disease type 2Z
- Autosomal dominant spastic paraplegia type 31
- Autosomal recessive centronuclear myopathy
- Distal anoctaminopathy
- FLNC-related handgrip and calf weakness-distal myopathy
- Gamma-sarcoglycan-related limb-girdle muscular dystrophy R5
- Kyphoscoliosis-lateral tongue atrophy-hereditary spastic paraplegia syndrome
- Moderate multiminicore disease with hand involvement
- Myopathy and diabetes mellitus
- Neutral lipid storage disease with myopathy
- Osgood-Schlatter disease
- Proximal myopathy with extrapyramidal signs
- Proximal spinal muscular atrophy
- Spinocerebellar ataxia type 13
- Spondyloepimetaphyseal dysplasia, Handigodu type
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Difficulty running
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.