Rare diseases · Sign or symptom
Bifid uvula
HP:0000193
What it means
Uvula separated into two parts most easily seen at the tip.
Rare diseases that can present with this65
Very common80–99%
5Common30–79%
23- Alobar holoprosencephaly
- Aneurysm-osteoarthritis syndrome
- Auriculocondylar syndrome
- Autosomal recessive complex spastic paraplegia due to Kennedy pathway dysfunction
- Autosomal recessive otospondylomegaepiphyseal dysplasia
- Blepharophimosis-intellectual disability syndrome, SBBYS type
- Cardiocranial syndrome, Pfeiffer type
- Hydrolethalus
- Hypogonadotropic hypogonadism-severe microcephaly-sensorineural hearing loss-dysmorphism syndrome
- Hypomandibular faciocranial dysostosis
- Lethal omphalocele-cleft palate syndrome
- Loeys-Dietz syndrome
- Microcephalic osteodysplastic primordial dwarfism types I and III
- Midline interhemispheric variant of holoprosencephaly
- Nephrosis-deafness-urinary tract-digital malformations syndrome
- Orofaciodigital syndrome type 4
- Osteopathia striata-cranial sclerosis syndrome
- Pai syndrome
- Pallister-Hall syndrome
- Semilobar holoprosencephaly
- Stickler syndrome
- Submucosal cleft palate
- Trisomy 8p syndrome
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Bifid palatine uvula · Cleft of uvula · Cleft uvula · Forked uvula · Split uvula · Uvula bifida
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.