Rare diseases · Sign or symptom
Abnormality of the wrist
Abnormalities of the wrists
HP:0003019
What it means
Abnormality of the wrist, the structure connecting the hand and the forearm.
Rare diseases that can present with this33
Very common80–99%
9- Craniofacial-deafness-hand syndrome
- Dermatoosteolysis, Kirghizian type
- Epiphyseal dysplasia-hearing loss-dysmorphism syndrome
- Kienbock disease
- Mesomelia-synostoses syndrome
- Microbrachycephaly-ptosis-cleft lip syndrome
- Multicentric carpo-tarsal osteolysis with or without nephropathy
- Satoyoshi syndrome
- Splenogonadal fusion-limb defects-micrognathia syndrome
Common30–79%
11- 17q24.2microdeletion syndrome
- Brachydactylous dwarfism, Mseleni type
- Cleft palate-stapes fixation-oligodontia syndrome
- Distal limb deficiencies-micrognathia syndrome
- Dystrophic epidermolysis bullosa pruriginosa
- Juberg-Hayward syndrome
- Laurin-Sandrow syndrome
- Müllerian duct anomalies-limb anomalies syndrome
- Occipital horn syndrome
- Rheumatoid factor-negative polyarticular juvenile idiopathic arthritis
- Ulnar-mammary syndrome
Sometimes5–29%
13- Auriculoosteodysplasia
- Congenital adrenal hyperplasia due to cytochrome P450 oxidoreductase deficiency
- Enthesitis-related juvenile idiopathic arthritis
- Farber disease
- Heart-hand syndrome type 2
- Hypermobile Ehlers-Danlos syndrome
- Isolated humero-radial synostosis
- Mesomelic dysplasia, Nievergelt type
and 5 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.