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Start free with EleplanImmunoglobulin A nephropathy
ORPHA:34145Disease
Also called Berger disease · IgA nephropathy
What it is
A rare glomerular disease, histologically characterized by glomerular mesangial deposits of IgA, often accompanied by IgG and complement C3 as well as mesangioproliferative changes, clinically mostly manifesting as oligosymptomatic glomerulonephritis, possibly infection-triggered macrohematuria and a variable course ranging from spontaneous remission to slow or rarely rapid progression to kidney failure.
Key facts
- Classified as
- Disease
Signs and symptoms
Common30–79%
5Sometimes5–29%
11- Ascites
- Celiac disease
- Cirrhosis
- Crackles
- Facial edema
- Foamy urine
- Glomerular crescent formation
- Glomerulonephritis
and 3 more in this range
These ranges are how often a sign appears across everyone diagnosed, not a prediction for one person — most people have some of these and not others. Orphanet also records findings that are specifically absent in this disease; those are in the data but not listed here.
ICD-10 codes
Cross-references
Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.
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