Polymyxin B Sulfate and Trimethoprim Sulfate is used in the treatment of pink eye, based on its FDA-labeled indications. It is a dihydrofolate reductase inhibitor antibacterial [epc].
Conjunctivitis is the medical name for pink eye. It involves inflammation of the outer layer of the eye and inside of the eyelid. It can cause swelling, itching, burning, discharge, and redness. Causes include: Bacterial or viral infection Allergies Substances that cause irritati… More on Pink Eye →
How Polymyxin B Sulfate and Trimethoprim Sulfate is used
INDICATIONS AND USAGE Polymyxin B Sulfate and Trimethoprim Ophthalmic Solution, USP is indicated in the treatment of surface ocular bacterial infections, including acute bacterial conjunctivitis, and blepharoconjunctivitis, caused by susceptible strains of the following microorganisms: Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, Streptococcus viridans, Haemophilus influenzae and Pseudomonas aeruginosa. * * Efficacy for this organism in this organ system was studied in fewer than 10 infections.
Dosage
DOSAGE AND ADMINISTRATION In mild to moderate infections, instill one drop in the affected eye(s) every three hours (maximum of 6 doses per day) for a period of 7 to 10 days.
Warnings
WARNINGS NOT FOR INJECTION INTO THE EYE. If a hypersensitivity reaction to polymyxin B sulfate and trimethoprim ophthalmic solution occurs, discontinue use. Polymyxin B sulfate and trimethoprim ophthalmic solution is not indicated for the prophylaxis or treatment of ophthalmia neonatorum.
Side effects
ADVERSE REACTIONS The most frequent adverse reaction to polymyxin B sulfate and trimethoprim ophthalmic solution is local irritation consisting of increased redness, burning, stinging, and/or itching. This may occur on instillation, within 48 hours, or at any time with extended use. There are also multiple reports of hypersensitivity reactions consisting of lid edema, itching, increased redness, tearing, and/or circumocular rash. Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis (SJS/TEN) and anaphylaxis have been reported. Photosensitivity has been reported in patients taking oral trimethoprim. To report SUSPECTED ADVERSE REACTIONS, contact Bausch & Lomb Incorporated at 1-800-553-5340 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch .
Is Polymyxin B Sulfate and Trimethoprim Sulfate used to treat Pink Eye?
Based on its FDA-labeled indications, Polymyxin B Sulfate and Trimethoprim Sulfate is used in the treatment of pink eye — dihydrofolate reductase inhibitor antibacterial [epc]. Use it only as prescribed — your clinician decides whether it's right for you.
What ICD-10 codes apply to Pink Eye?
Pink Eye is coded in ICD-10-CM as H10.
Informational only, drawn from FDA labeling and NIH MedlinePlus — not medical advice. Talk to your clinician about whether Polymyxin B Sulfate and Trimethoprim Sulfate is right for you.
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