Visceral heterotaxy

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Visceral heterotaxy

ORPHA:450Morphological anomaly

Also called Heterotaxy · Heterotaxy syndrome

What it is

A rare developmental defect during embryogenesis characterized by abnormal arrangement of the thoraco-abdominal organs across the left-right axis of the body. By definition, it does not include situs inversus totalis (total mirror-imagery).

Key facts

Prevalence
1-5 / 10 000 (at birth, United States)
Age of onset
Antenatal, Infancy, Neonatal
Inheritance
Autosomal dominant, Autosomal recessive, X-linked recessive
Classified as
Morphological anomaly

Prevalence figures describe populations, not individuals, and are often estimates from a single study. Where the figure is an incidence or a birth prevalence, it says so.

Genes reported in subtypes

GDF1

Orphanet records this gene on 1 more specific entry under this disorder, not on this entry itself:

A well-studied disease is usually split into subtypes, and the gene is curated on whichever one the evidence belongs to. Open a subtype to see which gene goes with it.

ICD-10 codes

Q89.3ICD-10 names this disease exactly — shared with 1 other rare disease

ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. A shared code identifies the group, not this disease — the ORPHAcode above is what identifies it.

Cross-references

GARD 10875MEDDRA 10067265MESH D059446MONDO 0018677MONDO 18677OMIM 270100OMIM 306955OMIM 601086OMIM 605376OMIM 606325OMIM 613751OMIM 614779OMIM 616749OMIM 617205OMIM 618948OMIM 619702UMLS C3178805

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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