Rare diseases · Sign or symptom
Waddling gait
Waddling walk
HP:0002515
What it means
Weakness of the hip girdle and upper thigh muscles, for instance in myopathies, leads to an instability of the pelvis on standing and walking. If the muscles extending the hip joint are affected, the posture in that joint becomes flexed and lumbar lordosis increases. The patients usually have difficulties standing up from a sitting position. Due to weakness in the gluteus medius muscle, the hip on the side of the swinging leg drops with each step (referred to as Trendelenburg sign). The gait appears waddling. The patients frequently attempt to counteract the dropping of the hip on the swinging side by bending the trunk towards the side which is in the stance phase (in the German language literature this is referred to as Duchenne sign). Similar gait patterns can be caused by orthopedic conditions when the origin and the insertion site of the gluteus medius muscle are closer to each other than normal, for instance due to a posttraumatic elevation of the trochanter or pseudarthrosis of the femoral neck.
Rare diseases that can present with this55
Very common80–99%
7Common30–79%
29- Alpha-dystroglycan-related limb-girdle muscular dystrophy R16
- Alpha-sarcoglycan-related limb-girdle muscular dystrophy R3
- Autosomal dominant Emery-Dreifuss muscular dystrophy
- Autosomal recessive centronuclear myopathy
- Autosomal recessive Emery-Dreifuss muscular dystrophy
- Autosomal recessive spastic paraplegia type 23
- Beta-sarcoglycan-related limb-girdle muscular dystrophy R4
- BICD2-related autosomal dominant childhood-onset proximal spinal muscular atrophy
- Camurati-Engelmann disease
- Distal anoctaminopathy
- Emery-Dreifuss muscular dystrophy
- FKRP-related limb-girdle muscular dystrophy R9
- Gamma-sarcoglycan-related limb-girdle muscular dystrophy R5
- Metaphyseal chondrodysplasia, Jansen type
- Multiple epiphyseal dysplasia type 4
- Osteoporosis-pseudoglioma syndrome
- Pelvis-shoulder dysplasia
- POMT1-related limb-girdle muscular dystrophy R11
- Progressive essential tremor-speech impairment-facial dysmorphism-intellectual disability-abnormal behavior syndrome
- Pseudoachondroplasia
- Pure mitochondrial myopathy
- Sagliker syndrome
- Severe intellectual disability and progressive spastic paraplegia
- Spastic paraplegia-severe developmental delay-epilepsy syndrome
- Spondyloepimetaphyseal dysplasia, matrilin-3 type
- Spondylometaphyseal dysplasia, Kozlowski type
- Synaptic congenital myasthenic syndrome
- TRAPPC11-related limb-girdle muscular dystrophy R18
- X-linked Emery-Dreifuss muscular dystrophy
Sometimes5–29%
19- Autosomal dominant adult-onset proximal spinal muscular atrophy
- Bethlem muscular dystrophy
- Childhood-onset nemaline myopathy
- Congenital myasthenic syndrome
- Congenital myasthenic syndrome with glycosylation defect
- Dysplasia of head of femur, Meyer type
- Gabriele-de Vries syndrome
- Hereditary hypophosphatemic rickets with hypercalciuria
and 11 more in this range
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.