Unusual Toxoplasma infection

What it means

Increased susceptibility to Toxoplasma gondii infections as manifested by recurrent or severe/invasive infection with Toxoplasma gondii, or by Toxoplasma gondii infection occurring in an unusual anatomical location.

Severe or unusual Toxoplasma gondii infections, including CNS toxoplasmosis, are primarily associated with severe T-cell deficiencies (both primary and secondary). This phenotype has also been specifically described in X-linked Hyper-IgM syndrome, where impaired T-cell signaling increases susceptibility to central nervous system involvement.

Part of the broader category

Also called: Unusual toxoplasmosis