Rare diseases · Sign or symptom
Retinal detachment
Detached retina
HP:0000541
What it means
Separation of the inner layers of the retina (neural retina) from the pigment epithelium.
In everyday care
Most people with this sign do not have a rare disease — it appears in common conditions far more often. These general reference pages cover the same topic:
Rare diseases that can present with this59
Very common80–99%
6Common30–79%
16- Blindness-scoliosis-arachnodactyly syndrome
- Coats disease
- Congenital primary aphakia
- Cutis marmorata telangiectatica congenita
- Donnai-Barrow syndrome
- Kniest dysplasia
- Marshall syndrome
- Microcephaly-facial dysmorphism-ocular anomalies-multiple congenital anomalies syndrome
- Musculocontractural Ehlers-Danlos syndrome
- Norrie disease
- Osteoporosis-pseudoglioma syndrome
- Proteus-like syndrome
- Revesz syndrome
- Sympathetic ophthalmia
- Vogt-Koyanagi-Harada disease
- Wagner disease
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions, and Orphanet separately records 2 diseases where this sign is specifically absent. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Tracking symptoms like this for someone? Eleplan keeps symptoms, diagnoses, medications and every specialist in one plan.
Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.