Rare diseases · Sign or symptom
Prominent nasal bridge
Elevated nasal bridge
HP:0000426
What it means
Anterior positioning of the nasal root in comparison to the usual positioning for age.
A prominent nasal bridge can occur irrespective of the width of the nasal bridge, and the width should be assessed separately. The nasal bridge becomes more prominent with age. Although the nasal root may be anteriorly placed without increasing the space between the eyes, prominence of the nasal bridge may be accompanied by Telecanthus or ocular Hypertelorism. If such findings are present these should be coded separately. Deep-set eyes may lead to the impression of a prominent nasal bridge, but this finding should be coded separately.
Rare diseases that can present with this105
Very common80–99%
34- 22q11.2deletion syndrome
- 2p15p16.1microdeletion syndrome
- Acrocraniofacial dysostosis
- Acrofacial dysostosis, Rodríguez type
- Aortic arch anomaly-facial dysmorphism-intellectual disability syndrome
- CEDNIK syndrome
- CK syndrome
- Cohen syndrome
- Craniolenticulosutural dysplasia
- Dentinogenesis imperfecta-short stature-hearing loss-intellectual disability syndrome
- Distal 16p11.2 microdeletion syndrome
- Distal duplication 15q syndrome
- Distal duplication 18q syndrome
- Distal duplication 6p syndrome
- Filippi syndrome
- Fryns-Smeets-Thiry syndrome
- Genitopatellar syndrome
- KAT6-related intellectual disability-craniofacial anomalies-cardiac defects syndrome
- Keipert syndrome
- Koolen-De Vries syndrome
- Monosomy 13q14 syndrome
- Mosaic trisomy 14 syndrome
- Nance-Horan syndrome
- Neurofaciodigitorenal syndrome
- Nijmegen breakage syndrome
- Pitt-Hopkins syndrome
- Potocki-Shaffer syndrome
- Prominent glabella-microcephaly-hypogenitalism syndrome
- Radioulnar synostosis-developmental delay-hypotonia syndrome
- Ring chromosome 7 syndrome
- SPECC1L-related hypertelorism syndrome
- Waardenburg syndrome
- X-linked intellectual disability, Cilliers type
- X-linked mandibulofacial dysostosis
Common30–79%
32- 20p13microdeletion syndrome
- 2q32q33deletion syndrome
- 3q29microdeletion syndrome
- Antenatal multiminicore disease with arthrogryposis multiplex congenita
- Autosomal recessive cutis laxa type 2A
- Autosomal recessive faciodigitogenital syndrome
- Burn-McKeown syndrome
- Corpus callosum agenesis-intellectual disability-coloboma-micrognathia syndrome
- Distal 17p13.1 microdeletion syndrome
- Distal duplication 5q syndrome
- DYRK1A-related intellectual disability syndrome due to 21q22.13q22.2 microdeletion
- Early-onset seizures-distal limb anomalies-facial dysmorphism-global developmental delay syndrome
- FRAXE intellectual disability
- Hypotonia-speech impairment-severe cognitive delay syndrome
- Intellectual disability-muscle weakness-short stature-facial dysmorphism syndrome
- Intellectual disability-myopathy-short stature-endocrine defect syndrome
- KBG syndrome
- Lujan-Fryns syndrome
- Macrocephaly-intellectual disability-left ventricular non compaction syndrome
- MEND syndrome
- Monosomy 13q34 syndrome
- Multiple pterygium-malignant hyperthermia syndrome
- Oculofaciocardiodental syndrome
- Peripheral demyelinating neuropathy-central dysmyelinating leukodystrophy-Waardenburg syndrome-Hirschsprung disease
- Pseudoaminopterin syndrome
- Saethre-Chotzen syndrome
- SATB2-associated syndrome due to a chromosomal rearrangement
- Say-Barber-Miller syndrome
- Schwartz-Jampel syndrome
- STAG1-related intellectual disability-facial dysmorphism-gastroesophageal reflux syndrome
- Urban-Rogers-Meyer syndrome
- Waardenburg-Shah syndrome
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Convex bridge of nose · Convex nasal bridge · High nasal bridge · Prominent bridge of nose · Prominent nasal root · Protruding bridge of nose · Protruding nasal bridge
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.