Rare diseases · Sign or symptom
Dysdiadochokinesis
Difficulty performing quick and alternating movements
HP:0002075
What it means
A type of ataxia characterized by the impairment of the ability to perform rapidly alternating movements, such as pronating and supinating his or her hand on the dorsum of the other hand as rapidly as possible.
Inability to perform rapid, alternating movements. Dysdiadochokinesis is generally related to a cerebellar lesion.
Rare diseases that can present with this33
Very common80–99%
3Common30–79%
18- Ataxia with vitamin E deficiency
- Autosomal recessive cerebellar ataxia-pyramidal signs-nystagmus-oculomotor apraxia syndrome
- Autosomal recessive congenital cerebellar ataxia due to MGLUR1 deficiency
- Autosomal recessive spastic paraplegia type 35
- Cerebellar ataxia with neuropathy and bilateral vestibular areflexia syndrome
- Cirrhosis-dystonia-polycythemia-hypermanganesemia syndrome
- Dentatorubral pallidoluysian atrophy
- Early-onset spastic ataxia-myoclonic epilepsy-neuropathy syndrome
- Mitochondrial myopathy-cerebellar ataxia-pigmentary retinopathy syndrome
- Paraneoplastic sensory ganglionopathy
- Spectrin-associated autosomal recessive cerebellar ataxia
- Spinocerebellar ataxia type 10
- Spinocerebellar ataxia type 29
- Spinocerebellar ataxia type 37
- Spinocerebellar ataxia type 40
- Spinocerebellar ataxia type 7
- Spinocerebellar ataxia with epilepsy
- X-linked progressive cerebellar ataxia
The range is how often this sign appears among people diagnosed with each disease — it is not a probability of having any of them. Many of these signs also occur in common, non-rare conditions. A sign on this page is a conversation to have with a clinician, not a conclusion.
Part of the broader category
Also called: Dysdiadochokinesia
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Start free with EleplanThis page uses the Human Phenotype Ontology (2026-06-23) — Human Phenotype Ontology Consortium, hpo.jax.org. Disease associations from Orphanet (INSERM), CC BY 4.0. Content is educational and is not medical advice.