Red cell aplasia-microcephaly-seizure-deve…

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Red cell aplasia-microcephaly-seizure-developmental delay syndrome

ORPHA:726036Disease

Also called BMFS due to TP53 gain-of-function variant · RCA-microcephaly-seizure-developmental delay syndrome · Germline p53 activation syndrome · BMFS5

What it is

Orphanet has not published a description for this disease yet. The identifiers, classification and cross-references below are still current.

Key facts

Prevalence
<1 / 1 000 000
Age of onset
Antenatal
Inheritance
Autosomal dominant
Classified as
Disease

Prevalence figures describe populations, not individuals, and are often estimates from a single study. Where the figure is an incidence or a birth prevalence, it says so.

Gene

TP53Disease-causing germline mutation(s)

Cross-references

OMIM 618165

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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