Primary acquired pure red cell aplasia

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Primary acquired pure red cell aplasia

ORPHA:98872Disease

Also called Primary acquired PRCA

What it is

A rare acquired aplastic anemia characterized by a severe normocytic anemia with normal peripheral leukocyte and platelet counts, reticulocytopenia, high serum ferritin and transferrin saturation levels and isolated, almost complete absence of erythroblasts in the bone marrow with normal granulopoesis and megakaryopoesis. It presents with signs of severe anemia (fatigue, lethargy, pallor, intolerance of physical exercise and exertional dyspnea) in the absence of hemorrhagic symptoms.

Key facts

Classified as
Disease

ICD-10 codes

D60.0filed under a broader ICD-10 category

Cross-references

GARD 10898UMLS C4707560

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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