Osteoblastoma

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Osteoblastoma

ORPHA:58040Disease

What it is

A rare, neoplastic disease characterized by a typically benign, locally aggressive, non self-limiting, osteoblastic bone tumor, usually located on the spine, proximal humerus and hip (although any bone may be involved), generally manifesting with slowly progressive, dull aching pain which is difficult to localize and is not relieved by nonsteroidal anti-inflammatory drugs or aspirin. Neurologic symptoms, such as cranial nerve palsies, myelopathy, neuralgia, radiculopathy, paraparesis or paraplegia, may be associated if the spine is involved. Imaging reveals a lytic (or mixed lytic and blastic) lesion with a radiolucent nidus (> 2 cm) associated with reactive sclerotic bone.

Key facts

Classified as
Disease

ICD-10 codes

D16.0ICD-10 uses a narrower term
D16.1ICD-10 uses a narrower term
D16.3ICD-10 uses a narrower term
D16.4ICD-10 uses a narrower term — shared with 5 other rare diseases
D16.5ICD-10 uses a narrower term — shared with 3 other rare diseases
D16.6ICD-10 uses a narrower term
D16.7ICD-10 uses a narrower term
D16.8ICD-10 uses a narrower term

ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. A shared code identifies the group, not this disease — the ORPHAcode above is what identifies it.

Related health topics

Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.

Cross-references

MESH D018215MONDO 0018936UMLS C0029417

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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