Isolated congenital sclerocornea

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Isolated congenital sclerocornea

ORPHA:91490Morphological anomaly

What it is

A rare corneal disorder characterized by non-inflammatory, non-progressive, bilateral ingrowth of vascularized, opaque scleral tissue into the peripheral cornea, obliterating the corneoscleral limbus and scleral sulcus. The condition is not associated with other ocular abnormalities.

Key facts

Inheritance
Autosomal dominant
Classified as
Morphological anomaly

Gene

GJA8Disease-causing germline mutation(s)

ICD-10 codes

Q13.3ICD-10 names this disease exactly

Cross-references

MONDO 0019629MONDO 19629OMIM 181700UMLS C0344533

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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