Hereditary hypercarotenemia and vitamin A…

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Hereditary hypercarotenemia and vitamin A deficiency

ORPHA:199285Disease

What it is

Hereditary hypercarotenemia and vitamin A deficiency is an extremely rare metabolic disorder characterized clinically by skin discoloration, elevated levels of carotene and low levels of vitamin A described in fewer than 5 patients to date.

Key facts

Prevalence
<1 / 1 000 000 (Europe)
Age of onset
Childhood, Infancy
Inheritance
Autosomal dominant
Classified as
Disease

Prevalence figures describe populations, not individuals, and are often estimates from a single study. Where the figure is an incidence or a birth prevalence, it says so.

Gene

BCO1Disease-causing germline mutation(s) (loss of function)

ICD-10 codes

E50.8filed under a broader ICD-10 category

Related health topics

Reached through the ICD-10 categories this disease is filed under, so these describe the broader group rather than this disease specifically.

Cross-references

MONDO 0007272OMIM 115300OMIM 277350UMLS C4511672

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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