Hemoglobin M disease

Caring for someone with this diagnosis? Eleplan keeps diagnoses, medications, documents and every specialist in one plan.

Start free with Eleplan

Hemoglobin M disease

ORPHA:330041Disease

Also called Autosomal dominant methemoglobinemia · M hemoglobinopathy

What it is

A rare hemoglobinopathy characterized by the presence of hemoglobin variants with structural abnormalities in the globin portion of the molecule which lead to auto-oxidation of heme iron, resulting in methemoglobinemia. Patients present with cyanosis for which no treatment is necessary. Mode of inheritance is autosomal dominant.

Key facts

Age of onset
No data available
Inheritance
Autosomal dominant
Classified as
Disease

Genes

HBA1Disease-causing germline mutation(s)
HBA2Disease-causing germline mutation(s)
HBBDisease-causing germline mutation(s)

ICD-10 codes

D74.0filed under a broader ICD-10 category — shared with 1 other rare disease

ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. A shared code identifies the group, not this disease — the ORPHAcode above is what identifies it.

Cross-references

GARD 13007MESH C581942MONDO 0018023OMIM 617971OMIM 617973UMLS C3665425

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

Powered by Eleplan

A rare diagnosis is just the start. Eleplan keeps the whole care plan in one place.

Diagnoses, medications, documents, appointments, and the whole care team — organized and always in sync, so you are not retelling the same story to every new specialist. With Ellie, your AI care assistant, on top of it. Free to start.