Familial isolated pituitary adenoma

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Familial isolated pituitary adenoma

ORPHA:314777Disease

Also called FIPA

What it is

A rare, hereditary endocrine tumor characterized by a benign pituitary adenoma that is either secreting (e.g. prolactin, growth hormone, thyroid stimulating hormone) or non-secreting. Symptoms may occur due to either the hormonal hypersecretion and/or the mass effect of the lesion on local structures in the brain.

Key facts

Age of onset
Adolescent, Adult, Childhood, Elderly, Infancy
Inheritance
Autosomal dominant
Classified as
Disease

Genes

AIPDisease-causing germline mutation(s)
CDH23Major susceptibility factor

ICD-10 codes

D35.2filed under a broader ICD-10 category — shared with 10 other rare diseases

ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. A shared code identifies the group, not this disease — the ORPHAcode above is what identifies it.

Cross-references

GARD 10959MESH C566321MONDO 0017824OMIM 102200OMIM 617540UMLS C2676191

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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