Early onset non-syndromic cataract

Caring for someone with this diagnosis? Eleplan keeps diagnoses, medications, documents and every specialist in one plan.

Start free with Eleplan

Early onset non-syndromic cataract

ORPHA:91492Disease

What it is

A rare, genetic, non-syndromic developmental defect of the eye disorder, with high clinical and genetic heterogeneity, most frequently characterized by bilateral, symmetrical, non-progressive cataracts which present at birth or in early-childhood. Additional ocular manifestations (e.g. anterior segment dysgenesis, colobomas, nystagmus, microcornea, microphthalmia, myopia) may be associated, however other organs/systems are usually not affected.

Key facts

Age of onset
Infancy, Neonatal
Inheritance
Autosomal dominant, Autosomal recessive, X-linked recessive
Classified as
Disease

Genes reported in subtypes

AGKCRYAACRYBB2CRYGBDNMBPEPHA2FYCO1GCNT2GJA8HSF4LEMD2LIM2LSSMIPNHSPGRMC1SIPA1L3

Orphanet records these genes on 1 more specific entry under this disorder, not on this entry itself:

A well-studied disease is usually split into subtypes, and the gene is curated on whichever one the evidence belongs to. Open a subtype to see which gene goes with it.

ICD-10 codes

Q12.0ICD-10 names this disease exactly — shared with 12 other rare diseases

ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. A shared code identifies the group, not this disease — the ORPHAcode above is what identifies it.

Cross-references

MONDO 0011060OMIM 115650OMIM 115660OMIM 115665OMIM 115700OMIM 115800OMIM 115900OMIM 116100OMIM 116200OMIM 116300OMIM 116400OMIM 116600OMIM 116700OMIM 116800OMIM 212500OMIM 302200OMIM 600881OMIM 601202OMIM 601547OMIM 601885OMIM 604219OMIM 604307OMIM 605387OMIM 605728OMIM 605749OMIM 607304OMIM 609376OMIM 609741OMIM 610019OMIM 610202OMIM 610425OMIM 610623OMIM 611391OMIM 611544OMIM 611597OMIM 613763OMIM 614422OMIM 614691OMIM 615188OMIM 615274OMIM 615277OMIM 616279OMIM 616509OMIM 616851UMLS C5925050

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

Powered by Eleplan

A rare diagnosis is just the start. Eleplan keeps the whole care plan in one place.

Diagnoses, medications, documents, appointments, and the whole care team — organized and always in sync, so you are not retelling the same story to every new specialist. With Ellie, your AI care assistant, on top of it. Free to start.