Congenital pulmonary airway malformation…

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Congenital pulmonary airway malformation type 2

ORPHA:280840Clinical subtype

Also called CCAM type 2 · CPAM type 2 · Congenital cystic adenomatoid malformation of the lung type 2 · Congenital cystic adenomatous malformation of the lung type 2 · Congenital cystic disease of the lung type 2

What it is

A rare subtype of congenital pulmonary airway malformation characterized by a multicystic mass of non-functioning lung tissue, consisting of small cysts of less than 2 cm in diameter. The lesions have intracystic communications, can be connected to the tracheobronchial tree, and are usually unilateral, involving a single lobe. The condition often presents with respiratory distress in the neonatal period or in infancy. It is frequently associated with other severe congenital anomalies, such as renal agenesis or dysgenesis, pulmonary sequestration, or cardiac abnormalities.

Key facts

Age of onset
Antenatal, Neonatal
Classified as
Clinical subtype

Recorded for the broader condition

Prevalence
1-9 / 100 000 (at birth, Europe)Congenital pulmonary airway malformation

Orphanet records these for the broader condition rather than for this specific form. They are a starting point, not a figure for this subtype — subtypes often differ, and some are defined by being rarer than the condition they sit under.

ICD-10 codes

Q33.0filed under a broader ICD-10 category — shared with 5 other rare diseases

ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. A shared code identifies the group, not this disease — the ORPHAcode above is what identifies it.

Cross-references

MONDO 0017250UMLS C5437761

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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