Congenital pulmonary airway malformation…

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Congenital pulmonary airway malformation type 0

ORPHA:280827Clinical subtype

Also called CPAM type 0 · Congenital cystic adenomatoid malformation of the lung type 0 · Congenital cystic adenomatous malformation of the lung type 0

What it is

A rare subtype of congenital pulmonary airway malformation characterized by global arrest of lung development with small, solid appearing lungs with a diffusely granular surface, histologically featuring bronchus-like structures with smooth muscle, glands, and numerous cartilage plates, embedded in loose, vascular mesenchymal tissue. The condition presents at birth and is incompatible with life.

Key facts

Age of onset
Antenatal, Neonatal
Classified as
Clinical subtype

Recorded for the broader condition

Prevalence
1-9 / 100 000 (at birth, Europe)Congenital pulmonary airway malformation

Orphanet records these for the broader condition rather than for this specific form. They are a starting point, not a figure for this subtype — subtypes often differ, and some are defined by being rarer than the condition they sit under.

ICD-10 codes

Q33.0filed under a broader ICD-10 category — shared with 5 other rare diseases

ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. A shared code identifies the group, not this disease — the ORPHAcode above is what identifies it.

Cross-references

MONDO 0017248UMLS C5437764

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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