Agenesis of the superior vena cava

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Agenesis of the superior vena cava

ORPHA:99114Morphological anomaly

Also called Absence of the SVC · Absence of the superior caval vein · Absence of the superior vena cava · Agenesis of the SVC · Agenesis of the superior caval vein

What it is

A rare congenital anomaly of the great veins characterized by unilateral or bilateral complete absence of the superior vena cava (SVC). Unilateral agenesis is mainly asymptomatic (most of the time diagnosed incidentally) and patients usually have otherwise normal heart structure. Bilateral agenesis, however, is frequently associated with other congenital cardiac anomalies and/or conduction abnormalities (such as tetralogy of Fallot, atrial septal defect) and typically present symptoms of SVC syndrome.

Key facts

Classified as
Morphological anomaly

ICD-10 codes

Q26.8filed under a broader ICD-10 category — shared with 14 other rare diseases

ICD-10 has no distinct code for most rare diseases, so many are filed under the nearest available one. A shared code identifies the group, not this disease — the ORPHAcode above is what identifies it.

Cross-references

MONDO 0020445UMLS C0265929

Orphadata Science: Free access data from Orphanet. © INSERM 1999. Data version 2026-06-23. Available under CC BY 4.0. This is a reference, not medical advice.

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