Medication side effect

Can Polysaccharide Iron Complex cause renal tubular necrosis?

Vitamin B12 [EPC]

Yes — renal tubular necrosis has been reported as a side effect of Polysaccharide Iron Complex in FDA adverse-event reports (FAERS) and product labeling. It is among the more frequently reported events for this medication. These are voluntary reports, so they show what's been reported, not how often it happens.

Reported adverse reactions

Adverse Reactions: Folic Acid: Allergic sensitizations have been reported following both oral and parenteral administration of folic acid. Ferrous Fumarate: Gastrointestinal disturbances (anorexia, nausea, diarrhea, constipation) occur occasionally, but are usually mild and may subside with continuation of therapy. Although the absorption of iron is best when taken between meals, giving PureVit DualFe Plus after meals may control occasional gastrointestinal disturbances. PureVit DualFe Plus is best absorbed when taken at bedtime. Call your doctor for medical advice about side effects. You may report suspected side effects to the FDA at 1-800-FDA-1088.

Warnings

WARNING: Accidental overdose of Iron-containing products is the leading cause of fatal poisoning of children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or Poison Control Center immediately. Folic acid alone is improper therapy in the treatment for pernicious anemia and other megaloblastic anemias where Vitamin B 12 is deficient.

Other reported side effects of Polysaccharide Iron Complex

Frequently asked questions

Is renal tubular necrosis a side effect of Polysaccharide Iron Complex?

Yes — renal tubular necrosis has been reported as a side effect of Polysaccharide Iron Complex in FDA adverse-event reports (FAERS) and/or its labeling. These are voluntary reports, so they show what's been reported, not how often it happens.

How common is renal tubular necrosis with Polysaccharide Iron Complex?

renal tubular necrosis is among the more frequently reported events for Polysaccharide Iron Complex in FAERS. Reporting volume isn't a true incidence rate — check the prescribing information for documented frequencies.

What should I do if I have renal tubular necrosis while taking Polysaccharide Iron Complex?

Don't stop a prescribed medication on your own. Tell your prescriber or pharmacist — they can tell you whether it's expected, whether it needs attention, and what to do next.

Informational only, drawn from FDA adverse-event reporting (FAERS) and labeling — not medical advice, and not proof a medication caused an effect. Talk to your clinician or pharmacist about any side effect.

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