Nickel Sulfate, Potassium Bromide, and Fumaric Acid for Psoriasis
ICD-10 L40
Nickel Sulfate, Potassium Bromide, and Fumaric Acid is used in the treatment of psoriasis, based on its FDA-labeled indications.
Psoriasis is a skin disease that causes itchy or sore patches of thick, red skin with silvery scales. You usually get the patches on your elbows, knees, scalp, back, face, palms and feet, but they can show up on other parts of your body. Some people who have psoriasis also get a … More on Psoriasis →
How Nickel Sulfate, Potassium Bromide, and Fumaric Acid is used
INDICATIONS PSORIZIDE ® Forte is indicated for the treatment of contact dermatitis due to nickel (metal/jewelry allergy,) dyshidrotic hand/foot eczema, and mild to severe psoriasis. It has been found to work well with a variety of combination therapies. Eczema, seborrhea and a variety of chronic pruritic inflammatory dermatoses generally respond well also.
Dosage
DOSAGE AND ADMINISTRATION Absorption of nickel sulphate is variable among individuals . For maximum absorption, tablets should be taken orally at the beginning of the day (or any convenient time after having taken nothing but water for at least 7 hours). Take nothing but water for one hour after taking medication to aid absorption. Weight Starting Dose Max Daily Dose 40-80 lbs ½ tablet 1 ½ tablet 80-120 lbs 1 tablet 3 tablets 120-160 lbs 1 ½ tablets 4 ½ tablets 160-200 lbs 2 tablets 6 tablets 200-240 lbs 2 ½ tablets 7 ½ tablets Over 240 lbs 3 tablets 9 tablets In the setting of renal impairment Dosage should be adjusted and serum nickel and bromide levels should be followed. Steady state trough level should be drawn prior to ingesting the day's dose after one week of dosing or at appropriate intervals. Target trough serum nickel level is 30-60 mcg/L. (Caution: post dose peak levels are unreliable.) Maintenance phase In order to maintain symptomatic relief, medication may be continued at the same or reduced initial phase dose level. Treatment duration depends on the individual. For allergic nickel dermatitis, continue 2 tablets 1 hour prior to breakfast for weeks 7 – 16. (Refer to Hypersensitivity section above). Some patients may require continued or intermittent repeated treatment to maintain nickel desensitization.
Warnings
WARNING Do not use if imprinted seal under bottle cap is missing or broken. Do not use if pregnant or nursing. If allergic to nickel or metal objects such as jewelry, see PRECAUTIONS for hypersensitivity information. Lactose intolerant patients may have gastrointestinal difficulty. This has very rarely been reported at the doses used.
Drug interactions
Drug Interactions There are no known drug interactions.
Side effects
ADVERSE REACTIONS PSORIZIDE ® Forte contains low doses of active ingredients. Therefore there are minimal known side effects. (see PRECAUTIONS for hypersensitivity information)
Is Nickel Sulfate, Potassium Bromide, and Fumaric Acid used to treat Psoriasis?
Based on its FDA-labeled indications, Nickel Sulfate, Potassium Bromide, and Fumaric Acid is used in the treatment of psoriasis. Use it only as prescribed — your clinician decides whether it's right for you.
What ICD-10 codes apply to Psoriasis?
Psoriasis is coded in ICD-10-CM as L40.
Informational only, drawn from FDA labeling and NIH MedlinePlus — not medical advice. Talk to your clinician about whether Nickel Sulfate, Potassium Bromide, and Fumaric Acid is right for you.
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