R65.21
BillableSevere sepsis with septic shock
R65.21 is the ICD-10-CM code for Severe sepsis with septic shock. It is a billable, specific code valid for reimbursement.
R00-R99 Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
Excludes1 — not coded here
- •postprocedural septic shock (T81.12-)
Frequently asked questions
- What is ICD-10 code R65.21?
- R65.21 is the ICD-10-CM code for "Severe sepsis with septic shock". It falls under R00-R99 Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified.
- Is R65.21 a billable code?
- Yes — R65.21 is a billable, specific ICD-10-CM code valid for reimbursement.
- What is excluded from R65.21?
- Excludes1 (not coded here): postprocedural septic shock (T81.12-).
Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.
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