R65.11

Billable

Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction

R65.11 is the ICD-10-CM code for Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction. It is a billable, specific code valid for reimbursement.

Status
Billable
Chapter
R00-R99
Parent
R65.1
Edition
FY2026

R00-R99 Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

Use additional code

  • code to identify specific acute organ dysfunction, such as:
  • acute kidney failure (N17.-)
  • acute respiratory failure (J96.0-)
  • critical illness myopathy (G72.81)
  • critical illness polyneuropathy (G62.81)
  • disseminated intravascular coagulopathy [DIC] (D65)
  • encephalopathy (metabolic) (septic) (G93.41)
  • hepatic failure (K72.0-)

Frequently asked questions

What is ICD-10 code R65.11?
R65.11 is the ICD-10-CM code for "Systemic inflammatory response syndrome (SIRS) of non-infectious origin with acute organ dysfunction". It falls under R00-R99 Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified.
Is R65.11 a billable code?
Yes — R65.11 is a billable, specific ICD-10-CM code valid for reimbursement.

Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.

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